Comprehensive Health Panel – Hormonal, Autoimmune, Metabolic & Nutritional Markers

Comprehensive Health Panel – Hormonal, Autoimmune, Metabolic & Nutritional Markers

A full overview of what each test measures, why it matters, and how results are typically interpreted in the UK.

Modern healthcare is moving toward personalised, preventative assessment. This comprehensive blood panel brings together thyroid markers, sex hormones, iron status, metabolic indicators, liver function, and essential vitamins, offering a broad picture of how the body is functioning.

This 16-marker panel includes:

  • anti-TG

  • anti-TPO

  • DHEA

  • Ferritin

  • FT3

  • FT4

  • HbA1c

  • Uric Acid

  • Full Blood Count (FBC)

  • Liver Function Tests (ALT, AST, ALP, Bilirubin, GGT)

  • Prolactin

  • Free Testosterone

  • TSH

  • Vitamin B12

  • Vitamin D (25-OH)

  • HOMA-IR (insulin resistance index)

Below is a clear and UK-safe explanation of each marker, what it shows, and typical reference ranges.
(Ranges vary between NHS and private labs.)

1. Anti-TG (Thyroglobulin Antibodies)

Why it matters

A marker of autoimmune activity affecting the thyroid.

Typical UK range:

  • Negative: < 60 IU/mL

What results may suggest:

  • Elevated levels may indicate autoimmune thyroid involvement.

2. Anti-TPO (Thyroid Peroxidase Antibodies)

Why it matters

One of the most sensitive markers of autoimmune thyroid activity.

Typical UK range:

  • Negative: < 34 IU/mL

What results may suggest:

  • High anti-TPO is common in autoimmune-related thyroid changes.

3. DHEA

Why it matters

A precursor hormone supporting energy, mood, stress resilience and libido.

Typical UK range (DHEA-S):

  • 35–430 µg/dL (age-dependent)

What results may indicate:

  • Low levels: age-related decline or stress.

  • High levels: physical training or supplementation.

4. Ferritin

Why it matters

Reflects iron stores. Low ferritin is extremely common, especially in women.

Typical UK ranges:

  • Women: 15–200 µg/L

  • Men: 30–400 µg/L

Interpretation:

  • Low ferritin: depleted iron stores.

  • High ferritin: inflammation or iron overload.

5. FT3 (Free Triiodothyronine)

Why it matters

Represents the active thyroid hormone.

UK range:

  • 3.1–6.8 pmol/L

What results may mean:

  • Low FT3: reduced hormonal activity.

  • High FT3: increased thyroid activity.

6. FT4 (Free Thyroxine)

UK range:

  • 12–22 pmol/L

Interpretation:

  • Low: reduced thyroid hormone production.

  • High: increased output or supplementation.

7. HbA1c (Glycated Haemoglobin)

A long-term measure of glucose regulation.

UK ranges:

  • Normal: < 42 mmol/mol

  • Pre-diabetes: 42–47 mmol/mol

  • Diabetes threshold: ≥ 48 mmol/mol

8. Uric Acid

Why it matters

Linked with metabolic balance and inflammation.

UK ranges:

  • Women: 140–360 µmol/L

  • Men: 200–430 µmol/L

9. Full Blood Count (FBC)

Key markers:

  • Haemoglobin

  • Red blood cells (RBC)

  • White blood cells (WBC)

  • Platelets

  • Red cell indices (MCV, MCH, MCHC)

FBC helps evaluate anaemia, immune activity, and overall blood health.

Example UK ranges:

  • Haemoglobin (women): 120–160 g/L

  • Haemoglobin (men): 130–180 g/L

  • WBC: 4.0–11.0 ×10⁹/L

10. Liver Function Tests (ALT, AST, ALP, Bilirubin, GGT)

Indicators of liver cell integrity, bile flow, detoxification and metabolic load.

Typical UK ranges:

  • ALT: 7–56 U/L

  • AST: 10–40 U/L

  • ALP: 30–130 U/L

  • Bilirubin: < 21 µmol/L

  • GGT: 0–60 U/L

11. Prolactin

Why it matters

Influenced by stress, sleep and exercise. Can affect cycles and libido.

UK range:

  • 100–500 mIU/L

12. Free Testosterone

Why it matters

Supports libido, motivation, muscle tone and cognitive focus.

Typical UK total testosterone reference:

  • 0.3–1.9 nmol/L
    (Free testosterone varies by method.)

13. TSH (Thyroid Stimulating Hormone)

Why it matters

Primary screening marker for thyroid function.

UK range:

  • 0.4–4.0 mIU/L
    (Some labs consider 0.5–2.5 “optimal”.)

14. Vitamin B12

Why it matters

Essential for energy, mood, nerve function and red blood cell formation.

UK range:

  • 200–900 ng/L

15. Vitamin D (25-Hydroxy)

Why it matters

Influences immunity, mood, bone strength and inflammation.

NICE UK ranges:

  • Deficient: < 25 nmol/L

  • Insufficient: 25–50 nmol/L

  • Sufficient: > 50 nmol/L

  • Optimal (functional): 75–125 nmol/L

16. HOMA-IR (Insulin Resistance Index)

Why it matters

Reflects how effectively the body responds to insulin.

Typical UK functional interpretation:

  • Optimal: < 1.0

  • Mild resistance: 1.0–2.0

  • Significant resistance: > 2.0

Why this 16-Marker Panel Is Valuable

Together, these tests give insight into:

  • thyroid function and autoimmune activity

  • hormonal balance

  • iron status and oxygen delivery

  • metabolic health and insulin sensitivity

  • liver function

  • vitamin sufficiency

  • inflammation and overall blood health

While these results do not diagnose any condition, they offer a powerful, detailed overview to support discussions with a healthcare professional.

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